How this page evolved

Every published version is kept. Each entry shows what changed and why. Earlier versions can be restored by moderators, but only if the material they rely on is still available.

1. Revision 3Sep 30, 2026, 6:25 PMLive

   Added the SELECT heart outcomes trial, weight regain after stopping, and FDA warnings on compounded products.

   • · Added section “What happens when you stop”.
   • · Added section “Side effects and safety”.
   • · 1 new source cited.
   • · Key takeaways were added.
   • · 4 new pieces of guidance for specific situations.
   • · 1 new open question.
2. Revision 2Sep 30, 2026, 6:25 PM

   First brief from the STEP 1 and SURMOUNT-1 trials.

   • · The main finding was rewritten.
   • · The finding is now labelled “evidence” (was “interpretation”).
   • · Added section “How much weight people lose”.
   • · Added section “Beyond weight: heart outcomes”.
   • · 4 new sources cited.
   • · The note on uncertainty changed.
   • · 2 new open questions.
3. Revision 1Sep 30, 2026, 6:25 PM

   Created the Sylo.

   • · First published version.